Synthetic Bone Graft
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What Is a Bone Graft?
A bone graft is a medical procedure used to repair or rebuild bone tissue when natural bone is insufficient to support normal function or healing. It is applied in several clinical situations, such as:
- Fracture repair
- Bone loss caused by trauma
- Bone infection (osteomyelitis)
- Bone cancer (tumor resection)
- Joint problems and arthritis
- Spinal fusion
- Dental implants
- Congenital bone deformities
Bone Regeneration Mechanisms
Successful bone regeneration relies on three complementary biological processes:
Osteoconduction
The process by which bone growth occurs on the surface of a scaffold or biomaterial, guiding the migration and organization of cells to form new bone tissue.
Osteoinduction
The stimulation of progenitor cells to differentiate into osteoblasts, which are responsible for the formation of new bone.
Osteogenesis
The natural process by which new bone tissue is formed, either through the body's own cells or with the help of synthetic materials.
An ideal bone graft should therefore be osteoconductive, osteoinductive, and osteogenic, providing a balance between resorption and regeneration, while ensuring mechanical strength and biocompatibility.
Synthetic Bone Substitutes
Synthetic bone substitutes are bioceramic materials engineered to replicate the mineral composition and structure of natural bone.
They act as biocompatible scaffolds that support new bone growth and are gradually resorbed as the natural bone regenerates.
At Medbone, we develop and manufacture high-purity calcium phosphate biomaterials through a patented process that mimets the microarchitecture of human bone.
Our materials are highly porous, with an interconnected structure that promotes efficient cell colonization and vascularization, key factors for effective bone regeneration.
Medbone’s synthetic bone substitutes are intended for the filling of non-load-bearing bone defects where the stability of the bone structure is not compromised.
Types of Bone Graft Materials
Bone substitutes are classified according to their origin and composition:
Alloplastic (Synthetic)
Laboratory-produced materials
Why Choose adbone®?
Medbone provides advanced synthetic bone substitute solutions for the pharmaceutical, biomedical, and industrial sectors.
Our materials are designed for predictable performance, consistency, and safety, making them ideal for research, testing, and product development environments.
Why Medbone?
Patented Technology
Microarchitecture that mimics human bone.
100% Synthetic
Free from animal or human-derived components.
Biocompatible and Safe
Made entirely from synthetic, non-animal and non-human materials.
Controlled Porosity and Composition
Reproducible and traceable, ensuring consistent quality.
Produced under ISO 13485
CE-marking and strict quality assurance processes.
Trusted by Industry and Research Partners Worldwide
Leading the way in synthetic bone graft solutions.
Learn More Call Us!
For more information about adbone® synthetic bone substitutes, please contact our team:
info@medbone.eu
or visit the Products section for technical data and detailed specifications.